By The Associated Press

Twins 3B Corey Koskie hangs on to keep from falling into the Tigers' dugout. (AP photo)

DETROIT - Minnesota set a Comerica Park record with six home runs, including two by light-hitting catcher Henry Blanco, and the Twins handed the Detroit Tigers their first loss of the season, 10-5 Saturday.

Luis Rivas, Corey Koskie, Jose Offerman and Lew Ford also connected for the Twins, giving starter Brad Radke plenty of support.

The Tigers, who opened last season 0-9 and lost an AL-record 119 games, had been the last unbeaten team in the majors at 4-0.

The previous record for home runs in a game at spacious Comerica Park was five, set by Boston on April 19, 2000, the year the park opened.

Radke (1-0) improved to 16-4 lifetime against Detroit. Five Twins relievers combined for four scoreless innings to finish it.

Jason Johnson (1-1) lost to the Twins for the first time in six career decisions, lasting just 2 1-3 innings.

White Sox 7, Yankees 3

NEW YORK - Mark Buehrle shut down New York on three singles over eight innings, and Magglio Ordonez and Jose Valentin homered to lead Chicago.

New York's All-Star-laden lineup has scored just 16 runs in five games since its season-opening Tokyo trip, going 2-3 against Tampa Bay and the White Sox.

Making his first career start at Yankee Stadium, Buehrle (1-0) allowed only a pair of unearned runs. He held tough when he had to, striking out Alex Rodriguez with two outs and two on in the fifth.

Jorge DePaula (0-1), filling in as New York's fifth starter while Jon Lieber rehabilitates his strained right groin, allowed five runs in the first two innings, but then got 12 straight outs before tiring in the seventh.

Royals 7, Indians 6, 10 innings

KANSAS CITY, Mo. - Aaron Guiel's two-out RBI single in the 10th inning gave Kansas City a victory over the Cleveland Indians, who blew a three-run lead in the ninth.

Matt Stairs singled off Rafael Betancourt (0-1) with two outs in the 10th, and pinch-runner Rich Thompson stole second. Guiel, who hit a two-run homer in the third inning, lined a game-winning single to center off Scott Stewart.

Scott Sullivan (1-0) got the win with one inning of scoreless relief.

Mike Sweeney capped a three-run rally in the ninth with a two-out, two-run single off David Riske. The Indians also blew save chances and lost in extra innings to Minnesota in their first two games of the year.

C.C. Sabathia threw eight solid innings and Travis Hafner went 3-for-4 with a home run and two RBIs to give the Indians a 6-3 lead going into the ninth.

Athletics 2, Mariners 1

OAKLAND, Calif. - Tim Hudson pitched a four-hitter for the first complete game in the majors this season and Oakland sent Seattle to its fifth straight loss.

Hudson (1-0) threw only 86 pitches and retired his final 11 batters. He struck out two and walked none in his 14th career complete game.

The Mariners, the only winless team in the majors, are 0-5 for the first time since 1994. Gil Meche (0-1) dropped to 0-4 in six career starts against the A's.

Oakland second baseman Mark Ellis will miss the entire season with a right shoulder injury that requires surgery.

Orioles 11, Devil Rays 3

ST. PETERSBURG, Fla. - Melvin Mora and Larry Bigbie each homered and drove in three runs, leading Baltimore over Tampa Bay.

Javy Lopez and Mora had four hits apiece. Mora hit a two-run homer in the fifth and an RBI single during a four-run sixth. Bigbie had a two-run single in the sixth and an eighth-inning solo homer.

Rafael Palmeiro and Lopez each had two RBIs for the Orioles. Reliever Rick Bauer (1-0) got the win by giving up one hit in five scoreless innings.

Tampa Bay's Eduardo Perez hit a two-run homer. Jeremi Gonzalez (0-2) gave up six runs and nine hits in five-plus innings.

Red Sox 4, Blue Jays 1

BOSTON - Pedro Martinez held Toronto to four hits over 7 2-3 innings to outpitch AL Cy Young winner Roy Halladay, and Boston scored all its runs on homers.

David Ortiz, Manny Ramirez and Mark Bellhorn connected for Boston, which bounced back from a 10-5 loss to the Blue Jays in its home opener Friday.

Martinez (1-1), who pitched pretty well on opening day but took the loss, struck out seven and walked two. He did not allow a runner past second base until Orlando Hudson homered in the seventh.

Keith Foulke got four outs for his second save.

Halladay (0-2) allowed three runs and seven hits in seven innings, striking out seven.

Rangers 12, Angels 6

ARLINGTON, Texas - Kenny Rogers won in his return to Texas, and the Rangers hit three home runs in a win over Anaheim.

Mark Teixeira, Michael Young and Hank Blalock, the twentysomething infielders the Rangers hope to build around, all homered in Texas' third straight win. Brad Fullmer had an RBI double and two RBI singles.

Rogers (1-0), the first Texas pitcher to have three stints with the team, struck out seven in six innings. All six runs and six of the seven hits he gave up came in the Anaheim fourth, and the 39-year-old left-hander allowed just one other baserunner.

John Lackey (0-1) gave up seven runs and nine hits in 3 2-3 innings.